Cancer biologists discover a new mechanism for an old drug

Doctors have long believed the cancer drug 5-fluorouracil works by damaging the building blocks of DNA, but researchers have now found that in certain cancers, it kills cells by interfering with RNA synthesis. The findings could help researchers design better drug combinations for colon and gastrointestinal cancers.

source https://www.sciencedaily.com/releases/2024/10/241007114913.htm