Study identifies Shisa7 gene as key driver in heroin addiction

Researchers have found a unique molecular signature and genes in the orbitofrontal cortex associated with heroin-seeking behavior. A preclinical rodent model implicated a gene called Shisa7 as the key predictor. A new study provides valuable insights into the neurobiological mechanisms underlying heroin addiction and may have implications for the development of innovative strategies to combat the ongoing opioid epidemic.

source https://www.sciencedaily.com/releases/2025/03/250326122927.htm