Scientists have uncovered new genetic rules that determine whether the immune system’s “killer” T cells remain powerful long-term defenders or become worn out and ineffective. By building a detailed genetic atlas of CD8 T cell states, researchers identified key molecular switches that push these cells toward either resilience or exhaustion. Remarkably, disabling just two previously unknown genes restored the tumor-killing power of exhausted T cells while preserving their ability to provide lasting immune protection.
source https://www.sciencedaily.com/releases/2026/03/260304184235.htm
Extreme coastal flooding surges worldwide as rising seas rewrite 100-year
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Human-caused sea-level rise has significantly increased the frequency of
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