Targeted immune intervention and stopping ART in model of SIV infection leads to control of viral replication and reservoirs

Researchers have shown unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The success of this immune-based approach follows the research team's identification of the mechanisms of action for PD1 and IL-10, molecules known to regulate HIV persistence and immune dysfunction.

source https://www.sciencedaily.com/releases/2024/09/240912161720.htm